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What medicine can be taken to dissolve stones?

2025-11-06 13:24:28 healthy

What medicine should be taken to turn stones away: hot topics and structured guide on the Internet in the past 10 days

Recently, drug selection for stone treatment has become a hot topic on the Internet. Combining the entire Internet search data and medical guidelines in the past 10 days, this article compiled a structured medication guide to help patients scientifically deal with stone problems.

1. Current hot-search list of stone treatment drugs

What medicine can be taken to dissolve stones?

Drug nameHot search indexApplicable stone types
Sodium Potassium Hydrogen Citrate Granules48500uric acid stones
α-mercaptopropionylglycine32000cystine stones
sodium bicarbonate tablets27800Uric acid/cystine stones
Allopurinol tablets19500Uric acid stones (lowering uric acid)
Paishi granules (Chinese patent medicine)56200Adjuvant treatment for small stones

2. Drug treatment options for different types of stones

Stone typedrug of choiceCourse of treatmentThings to note
uric acid stonesCitrate preparations3-6 monthsNeed to cooperate with urine alkalinization
cystine stonesα-mercaptopropionylglycinelong term maintenanceNeed to drink lots of water
calcium oxalate stonesThiazide diureticsindividualizationsodium restricted diet
calcium phosphate stonesAcetylhydroxyproline6-12 monthsControl urinary tract infections

3. Core precautions for drug use

1.Diagnosis first: The composition of the stones must be clarified through imaging and urinalysis before medication is administered.

2.dose control: Citrate preparations need to maintain urine pH at 6.5-7.0. Excessive use may induce other stones.

3.combination therapy: Medical treatment needs to be combined with drinking 2.5-3 liters of water per day and controlling diet (such as uric acid stones require a low-purine diet).

4.Regular review: B-ultrasound and urinalysis need to be reviewed every 3 months to evaluate the treatment effect.

4. The latest treatment progress in 2023

New drug nameR&D stageMechanism of actionEstimated time to market
LumasiranPhase III clinicalInhibit oxalic acid production2024
TopiroxostatAlready on the market (Japan)Selective xanthine oxidase inhibitor-

5. Key points of expert consensus

1. For stones with a diameter of less than 5 mm, drug removal can be attempted, and for stones with a diameter of > 10 mm, extracorporeal lithotripsy or surgery should be considered.

2. The effectiveness of Paishi Granules, a Chinese patent medicine, is about 68% for stones with a diameter of less than 4 mm, but it needs to be treated with Western medicine.

3. Taking alkaline drugs at night can better control the pH fluctuation of morning urine.

Warm reminder:The data in this article come from public medical literature and Internet hot search statistics. The specific medication plan needs to be formulated after evaluation by a urologist. Sudden renal colic or fever requires immediate emergency treatment.

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